What the requirements for the greyed-out skills/perks?

What the requirements for the greyed-out skills/perks? - A Woman Performing a Backflip

Alpha 17 comes with a completely revamped skill/perk system. A number of skills/perks, namely the crafting ones, are greyed out and unavailable at the beginning. I can't see how to unlock these skills/perks on the current UI. What are the requirements for these skills/perks?

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